LpL^p-boundedness properties for the maximal operators for semigroups associated with Bessel and Laguerre operators

In this paper we prove that the generalized (in the sense of Caffarelli and Calder\'on) maximal operators associated with heat semigroups for Bessel and Laguerre operators are weak type (1,1). Our results include other known ones and our proofs are simpler than the ones for the known special cases.Comment: 8 page

A Rule-Based Expert System for Teachers’ Certification in the Use of Learning Management Systems

In recent years and accelerated by the arrival of the COVID-19 pandemic, Learning Management Systems (LMS) are increasingly used as a complement to university teaching. LMS provide an important number of resources and activities that teachers can freely select to complement their teaching, which means courses with different usage patterns difficult to characterize. This study proposes an expert system to automatically classify courses and certify teachers’ LMS competence from LMS logs. The proposed system uses clustering to stablish the classification scheme. From the output of this algorithm, it defines the rules used to classify courses. Data registered from a university virtual campus with 3,303 courses and two million interactive events have been used to obtain the classification scheme and rules. The system has been validated against a group of experts. Results show that it performs successfully. Therefore, it can be concluded that the system can automatically and satisfactorily evaluate and certify the teachers’ LMS competence evidenced in their courses

Intoxicação por cobre em ovinos na região de Franca - SP alimentados com ração de bovinos de leite

Intoxicação crônica por cobre foi observada em um rebanho de 20 ovinos no município de Franca, São Paulo. Três meses após o início do arraçoamento com feno e ração concentrada peletizada para bovinos de leite, seis animais apresentaram anorexia, icterícia severa e urina marrom escura, e vieram a óbito. Diagnosticou-se doença hemolítica com base em sinais clínicos, alterações macroscópicas observadas na necropsia e observações histológicas. À necropsia todos os ovinos apresentaram icterícia severa, fígado amarelado com padrão lobular evidente e rins escuros. As principais alterações histológicas incluíram necrose hepática periacinar e nefrose hemoglobinúrica. Acúmulos de cobre foram demonstrados nos hepatócitos e macrófagos pela coloração rodamina e níveis elevados de cobre mediante espectrofotometria de absorção atômica no soro, fígado e rins de dois ovinos afetados e na ração fornecida

Clustering of LMS Use Strategies with Autoencoders

Learning Management Systems provide teachers with many functionalities to offer materials to students, interact with them and manage their courses. Recognizing teachers’ instructing styles from their course designs would allow recommendations and best practices to be made. We propose a method that determines teaching style in an unsupervised way from the course structure and use patterns. We define a course classification approach based on deep learning and clustering. We first use an autoencoder to reduce the dimensionality of the input data, while extracting the most important characteristics; thus, we obtain a latent representation of the courses. We then apply clustering techniques to the latent data to group courses based on their use patterns. The results show that this technique improves the clustering performance while avoiding the manual data pre-processing work. Furthermore, the obtained model defines seven course typologies that are clearly related to different use patterns of Learning Management Systems

Displasia renal em um bezerro Limousin

Descreve-se um caso de displasia renal em um bezerro Limousin, macho, de quatro meses. O animal apresentava perda de peso, baixa taxa de crescimento, anorexia, apatia, diarréia escura fétida e uremia, sem melhora apesar de tratamento. O bezerro foi sacrificado para interromper o sofrimento adicional e submetido à necropsia. Ao exame foi observado que os rins estavam pequenos, firmes, pálidos e com superfície rugosa. A cápsula estava aderida à uma superfície subcapsular irregular. O córtex tinha aparência difusamente pálida e fibrosa e apresentava múltiplos focos brancos de fibrose. A junção córtico-medular estava indistinta. O exame histologico dos rins revelou múltiplos glomérulos imaturos com núcleo periférico, capilares inaparentes e padrão arbóreo. O córtex renal apresentou túbulos primitivos com epitélio cubóide ou cilíndrico envolvido por mesênquima corado somente pelo alcian blue e não pelo tricrômico de Masson. Foi também observada leve fibrose intersticial na medula renal. Os rins mostravam estruturas em estágio inapropriado de desenvolvimento ou anômalas

The causes, consequences, and treatment of left or right heart failure

Chronic heart failure (HF) is a cardiovascular disease of cardinal importance because of several factors: a) an increasing occurrence due to the aging of the population, primary and secondary prevention of cardiovascular events, and modern advances in therapy, b) a bad prognosis: around 65% of patients are dead within 5 years of diagnosis, c) a high economic cost: HF accounts for 1% to 2% of total health care expenditure. This review focuses on the main causes, consequences in terms of morbidity, mortality and costs and treatment of HF

Perosomus elumbis in a sheep in Brazil

Perosomus elumbis designa um conjunto raro de anomalias congênitas que primariamente incluem agenesia parcial da medula espinhal e vértebras lombossacrais. O presente relato descreve a ocorrência da enfermidade em um ovino neonato no Brasil.Perosomus elumbis designates a set of rare abnormal congenital abnormalities that primarily includes partial agenesis of spinal cord and lumbosacral vertebrae. The present paper reports the occurrence of the disease in a neonate sheep in Brazil

Sequestration and biosynthesis of cyanogenic glucosides in passion vine butterflies and consequences for the diversification of their host plants.

The colorful heliconiine butterflies are distasteful to predators due to their content of defense compounds called cyanogenic glucosides (CNglcs), which they biosynthesize from aliphatic amino acids. Heliconiine larvae feed exclusively on Passiflora plants where ~30 kinds of CNglcs have been reported. Among them, some CNglcs derived from cyclopentenyl glycine can be sequestered by some Heliconius species. In order to understand the evolution of biosynthesis and sequestration of CNglcs in these butterflies and its consequences for their arms race with Passiflora plants, we analyzed the CNglc distribution in selected heliconiine and Passiflora species. Sequestration of cyclopentenyl CNglcs is not an exclusive trait of Heliconius, since these compounds were present in other heliconiines such as Philaethria, Dryas and Agraulis, and in more distantly related genera Cethosia and Euptoieta. Thus, it is likely that the ability to sequester cyclopentenyl CNglcs arose in an ancestor of the Heliconiinae subfamily. Biosynthesis of aliphatic CNglcs is widespread in these butterflies, although some species from the sara-sapho group seem to have lost this ability. The CNglc distribution within Passiflora suggests that they might have diversified their cyanogenic profile to escape heliconiine herbivory. This systematic analysis improves our understanding on the evolution of cyanogenesis in the heliconiine-Passiflora system